- Aug 2
Our Industry-leading HuProt™ microarray contains
HuProt is quality confirmed with anti-GST QA/QC. Successful folding has been demonstrated by kinase autophosphorylation assay.HUPROT MICROARRAY
HuScan™ - Human PhIP-Seq Antibody Profiling Services
Human proteome epitope-level autoantibody profiling service via T7 phage display and immunoprecipitation sequencing (PhIP-Seq).HUSCAN PHIP-SEQ
CDI Labs Autoantibody Profiling Services
CDI Labs offers high-throughput focused array services to validate autoantibody signatures discovered with the HuProt Microarray.HUPROT SERVICES
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GST-purified validated full-length recombinant proteins
Purified virion display correctly-folded membrane-embedded GPCRs
Detects antibodies against 48,921 unique human proteins and protein isoforms
Detects antibodies against 50,135 unique murine proteins and protein isoforms
Detects antibodies against >68,000 vertebrate viral protein sequences
HuScan, MouseScan and VirScan are provided exclusively by CDI Labs Canada.
The serome is the total secreted antibody repertoire of a single individual; each serome is unique and created by a person's lifetime of adaptive immune experiences. The goal of the emerging scientific field of 'autoantibody seromics' is to understand the largest impacts of the serome on human health, disease, and clinical outcomes.
We start with sequence-confirmed plasmids, then individually express and GST-purify proteins from S. cerevisiae. Piezolelectric printing is used to spot these in duplicate alongside controls. Quality is confirmed with anti-GST QA/QC. Successful folding demonstrated by kinase autophosphorylation assay.
With over 200 publications (and growing), our antibody seromics solutions and HuProt array continue to play a key role in life sciences by contributing to critical studies that help accelerate research, advance discoveries, and translate discoveries to novel products that improve human health.
Our customer base continues to expand throughout North America, Europe, and Asia Pacific, and is a testament to the quality and consistency of our products and services.
Funded by NIH Common Fund Support for the Development of Protein Capture Reagents and Technologies, the HuProt Protein Microarray was created by CDI Labs co-founders Jef Boeke, Heng Zhu, Dan Eichinger, and Seth Blackshaw, faculty members at the High Throughput Biology (HIT) Center at the Johns Hopkins University School of Medicine.
Faculty of MedicineResearch Institution
Senior ScientistBiotech Research
Louise Malle, Dusan Bogunovic, et. al.
Paul Johannet, Iman Osman, et. al.
Marie Naigeon, Nathalie Chaput, et. al.
Tom Le Voyer, Anne Puel, et. al.
T. V. Clendenen, Y. Chen, et. al.
Subir Biswas, Jose R. Conejo-Garcia, et. al.
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