Unleash the Power of Autoantibody Profiling and Biomarker Discovery

The Most Comprehensive Antigen-specific Assay Available for Human Proteome Analysis

Phage ImmunoPrecipitation Sequencing (PhIP-Seq) is a powerful method of multiplexed analysis that combines high-throughput DNA sequencing with next-generation proteomics

Unlock the complete story of human immune responses with HuScan® PhIP-Seq. This groundbreaking technology represents the most comprehensive antigen-specific assay available today, capable of analyzing an individual's entire antibody repertoire against the complete human proteome in a single, streamlined assay. By leveraging advanced Phage Display ImmunoPrecipitation Sequencing (PhIP-Seq), HuScan simultaneously profiles autoantibodies at the epitope level across 48,921 proteins and isoforms from the NCBI RefSeq database, providing unprecedented insights into immune exposure histories, autoimmune pathways, and potential therapeutic targets.

PhIP-Seq allows researchers to determine what antibodies were created by an individual’s unique history of immune exposures. PhIP-Seq is the highest-coverage antigen-specific assay yet developed, able to detect antibodies versus virtually any antigen via overlapping long peptides. HuScan® enables simultaneous epitope-level autoantibody profiling versus an entire NCBI human proteome (48,921 proteins and isoforms) via phage-display and immunoprecipitation sequencing.